BDBM50523937 CHEMBL4473971

SMILES CCCC(CCC)(c1ccc(N)c(C)c1)c1ccc(O)c(C)c1

InChI Key InChIKey=ZXIJQUDVFWUYHK-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50523937   

TargetEstrogen receptor(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50523937(CHEMBL4473971)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at FLAG-tagged ERalpha (unknown origin) expressed in HEK293 cells assessed as induction of ER-alpha-mediated transcriptional activit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50523937(CHEMBL4473971)
Affinity DataIC50:  8.10nMAssay Description:Antagonist activity at FLAG-tagged ERalpha (unknown origin) expressed in HEK293 cells assessed as reduction in E2-induced ER-alpha-mediated transcrip...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50523937(CHEMBL4473971)
Affinity DataIC50:  1.70nMAssay Description:Binding affinity to GST-tagged human ER alpha ligand-binding domain by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50523937(CHEMBL4473971)
Affinity DataEC50:  9nMAssay Description:Selective estrogen receptor down-regulator activity at FLAG-tagged ERalpha (unknown origin) expressed in HEK293 cells assessed as induction of ERalph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed