BDBM50524338 CHEMBL4468000
SMILES NCc1cccc(c1)-c1cccc(COc2ccccc2CC(O)=O)c1
InChI Key InChIKey=CFIDHIDGDXATPD-UHFFFAOYSA-N
Data 14 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50524338
Affinity DataIC50: 270nMAssay Description:Inhibition of FD-mediated alternative complementation pathway in 50% human whole blood assessed as reduction in zymosan-induced membrane-attack compl...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of F11a (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of 2-((1E,3E,5E)-5-(1-(6-((((3S,5S)-1-((1-carbamoyl-1H-indol-3-yl)carbamoyl)-5-((3-chloro-2-fluorobenzyl)carbamoyl)-3-fluoropyrrolidin-3-y...More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of tryptase-beta2 (unknown origin)More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Human)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 770nMAssay Description:Inhibition of urokinase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 630nMAssay Description:Inhibition of human F11a using D-Leu-Pro-Arg*Rh110-D-Pro as substrate preincubated for 60 mins followed by substrate addition and measured after 60 m...More data for this Ligand-Target Pair
Affinity DataIC50: 640nMAssay Description:Inhibition of human factor 11a by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of PKL (unknown origin) using D-Leu-Pro-Arg*Rh110-D-Pro as substrate preincubated for 60 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERG by Qpatch assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human F7a using fluorescent peptide as substrate by florescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human plasmin using fluorescent peptide as substrate by florescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonist activity at human SUCNR1 expressed in human CHEM1 cells incubated for 60 mins in presence of [35S]GTPgammaS by scintillation proximity ass...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human CFD expressed in Escherichia coli incubated up to 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human complement FD by TR-FRET assayMore data for this Ligand-Target Pair