BDBM50524839 CHEMBL4466328

SMILES CC(C)C[C@H](N1CCN[C@@H](CC(C)C)C1=O)C(=O)N1CCN([C@@H](CCC(N)=O)C(N)=O)C(=O)[C@@H]1C

InChI Key InChIKey=FMTAQWMOLHFOLT-UHFFFAOYSA-N

Data  2 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50524839   

TargetHistone acetyltransferase p300/Hypoxia-inducible factor 1-alpha(Human)
Institute of Science Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524839BDBM50524839(CHEMBL4466328)
Affinity DataIC50: 51nMAssay Description:Inhibition of HIF-1alpha(unknown origin)/human p300 CH1 domain (323 to 423 residues) PPI extracted from Escherichia coli incubated for 1 hr by Spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Institute of Science Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524839BDBM50524839(CHEMBL4466328)
Affinity DataIC50: 530nMAssay Description:Inhibition of p300 CH1 domain (unknown origin) by tryptophan fluorescence spectroscopy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCREB-binding protein/Histone acetyltransferase p300(Human)
Medical University of Warsaw

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524839BDBM50524839(CHEMBL4466328)
Affinity DataKd:  530nMAssay Description:Binding affinity to p300-CBP (unknown origin) protein protein interaction assessed as dissociation constant by tryptophan fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Institute of Science Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524839BDBM50524839(CHEMBL4466328)
Affinity DataKd:  530nMAssay Description:Binding affinity to p300-CH1 domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Institute of Science Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524839BDBM50524839(CHEMBL4466328)
Affinity DataKd:  530nMAssay Description:Binding affinity to p300 CH1 domain (unknown origin) by tryptophan fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed