BDBM50525115 CHEMBL4582879

SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.C[C@H](NC(=O)[C@H](CCCCN)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCCN1CCN(CCCCC2CCN(CC(=O)N3c4ccccc4NC(=O)c4ccccc34)CC2)CC1

InChI Key InChIKey=ODQRSVBGWMYGDJ-CPEAVJPRSA-N

Data  7 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50525115   

TargetMuscarinic acetylcholine receptor M2(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50525115(CHEMBL4582879)
Affinity DataKi:  0.0631nMAssay Description:Competitive displacement of [3H]-NMS from human muscarinic M2 receptor expressed in CHO-K9 cells using 0.2 nM [3H]-NMS after 3 hrs by microbeta2 scin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M2(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50525115(CHEMBL4582879)
Affinity DataKi:  0.0631nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 receptor expressed in CHO-K9 cells after 3 hrs by microbeta2 scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M2(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50525115(CHEMBL4582879)
Affinity DataKi:  0.0794nMAssay Description:Competitive displacement of [3H]-NMS from human muscarinic M2 receptor expressed in CHO-K9 cells using 2 nM [3H]-NMS after 3 hrs by microbeta2 scinti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M4(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50525115(CHEMBL4582879)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]-NMS from human muscarinic M4 receptor expressed in CHO-K9 cells after 3 hrs by microbeta2 scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50525115(CHEMBL4582879)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]-NMS from human muscarinic M1 receptor expressed in CHO-K9 cells after 3 hrs by microbeta2 scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50525115(CHEMBL4582879)
Affinity DataKi:  110nMAssay Description:Displacement of [3H]-NMS from human muscarinic M3 receptor expressed in CHO-K9 cells after 3 hrs by microbeta2 scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M5(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50525115(CHEMBL4582879)
Affinity DataKi:  295nMAssay Description:Displacement of [3H]-NMS from human muscarinic M5 receptor expressed in CHO-K9 cells after 3 hrs by microbeta2 scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M2(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50525115(CHEMBL4582879)
Affinity DataIC50:  0.191nMAssay Description:Competitive displacement of [3H]-NMS from human muscarinic M2 receptor expressed in CHO-K9 cells using 0.2 nM [3H]-NMS after 3 hrs by microbeta2 scin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M2(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50525115(CHEMBL4582879)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at human muscarinic M2 receptor expressed in HEK293 cells co-expressing HA-Galphaq/i5 assessed as inhibition of carbachol-induced...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M2(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50525115(CHEMBL4582879)
Affinity DataIC50:  1.80nMAssay Description:Competitive displacement of [3H]-NMS from human muscarinic M2 receptor expressed in CHO-K9 cells using 2 nM [3H]-NMS after 3 hrs by microbeta2 scinti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed