BDBM50525554 CHEMBL4551724

SMILES CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)C(=O)NCc1ccccc1

InChI Key InChIKey=RSOWIFAFJKVGTQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50525554   

TargetProteasome subunit beta type-5(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50525554(CHEMBL4551724)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of 20S proteosome beta 5 purified from human HCT116 cells using Suc-LLVY-AMC as substrate incubated for 30 to 120 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50525554(CHEMBL4551724)
Affinity DataIC50: 2.15E+4nMAssay Description:Inhibition of 20S proteosome beta 2 purified from human HCT116 cells using Boc-LRR-AMC as substrate incubated for 30 to 120 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50525554(CHEMBL4551724)
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of 20S proteosome beta 1 purified from human HCT116 cells using Z-LLE-AMC as substrate incubated for 30 to 120 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed