BDBM50525563 CHEMBL4588752

SMILES CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)C(=O)NCc1ccccc1

InChI Key InChIKey=PXYJCABTNBGZIO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50525563   

TargetProteasome subunit beta type-2(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50525563(CHEMBL4588752)
Affinity DataIC50: 2.11E+3nMAssay Description:Inhibition of 20S proteosome beta 2 purified from human HCT116 cells using Boc-LRR-AMC as substrate incubated for 30 to 120 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50525563(CHEMBL4588752)
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of 20S proteosome beta 1 purified from human HCT116 cells using Z-LLE-AMC as substrate incubated for 30 to 120 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50525563(CHEMBL4588752)
Affinity DataIC50: 6.33E+4nMAssay Description:Inhibition of 20S proteosome beta 5 purified from human HCT116 cells using Suc-LLVY-AMC as substrate incubated for 30 to 120 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed