BDBM50525584 CHEMBL4453941
SMILES CC(C)(C#N)c1cccc(n1)-c1ccnc2[nH]ccc12
InChI Key InChIKey=FHISAROGPSYNME-UHFFFAOYSA-N
Data 9 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50525584
Affinity DataKi: 3nMAssay Description:Inhibition of human recombinant full length His tagged PKC theta expressed in baculovirus using ERMRPRKRQGSVRRRV peptide as substrate incubated for 6...More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibition of ROCK (unknown origin) using Myelin Basic Protein as substrate incubated for 60 mins in presence of [33P] gammaATP by microbeta liquid s...More data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Inhibition of recombinant full length PKC delta (unknown origin) using ERMRPRKR- QGSVRRRV peptide as substrate measured after 15 mins in presence of ...More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Inhibition of JAK2 (unknown origin) using polyE4Y peptide as substrate incubated for 60 mins in presence of [33P] gammaATP by microbeta liquid scinti...More data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Inhibition of FLT3 (unknown origin) using polyE4Y peptide as substrate incubated for 60 mins in presence of [33P] gammaATP by microbeta liquid scinti...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 110nMAssay Description:Inhibition of protein kinase A (unknown origin) using Kemptide (LRRASLG) as substrate incubated for 15 mins in presence of ATP by spectrophotometric ...More data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Inhibition of recombinant full length PKC alpha (unknown origin) using RRRRRKGSFKRKA peptide as substrate measured after 15 mins in presence of ATP b...More data for this Ligand-Target Pair
Affinity DataKi: 210nMAssay Description:Inhibition of GSK-3beta (unknown origin) using HSSPHQS(PO3H2)EDEEE peptide as substrate measured after 15 mins in presence of ATP by spectrophotometr...More data for this Ligand-Target Pair