BDBM50525934 CHEMBL4529789
SMILES C[C@H](Nc1c(-c2nc3c(F)cc(cc3[nH]2)N2CCOCC2)c(=O)[nH]c2cn(C)nc12)c1ncccn1
InChI Key InChIKey=GLZXNTQZIPGNHO-ZDUSSCGKSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50525934
Affinity DataIC50: 0.480nMAssay Description:Inhibition of human FGFR3 wild-type using FL-peptide substrate measured after 50 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of FGFR3 V555M mutant (unknown origin) expressed in mouse NIH/3T3 cells overexpressing FGFR3-V555M mutant TACC3 assessed as inhibition of ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.90nMAssay Description:Inhibition of wild-type FGFR3 (unknown origin) expressed in mouse NIH/3T3 cells overexpressing wild type FGFR3-TACC3 assessed as inhibition of cell p...More data for this Ligand-Target Pair
Affinity DataIC50: 0.410nMAssay Description:Inhibition of human FGFR3 V555M mutant using FL-peptide substrate measured after 45 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair