BDBM50526627 (-)-Silychristin::CHEMBL589325

SMILES COc1cc(ccc1O)[C@H]1Oc2c(cc(cc2O)[C@H]2Oc3cc(O)cc(O)c3C(=O)[C@@H]2O)[C@@H]1CO

InChI Key InChIKey=BMLIIPOXVWESJG-KEDVUCMTSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50526627   

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526627((-)-Silychristin | CHEMBL589325)
Affinity DataKi:  2.80E+3nMAssay Description:Mixed type inhibition of monophenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-Tyrosine substrate by UV...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526627((-)-Silychristin | CHEMBL589325)
Affinity DataKi:  2.80E+3nMAssay Description:Inhibition of monophenolase activity of mushroom tyrosinase assessed as inhibition constant for free enzyme-inhibitor complex by measuring reduction ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526627((-)-Silychristin | CHEMBL589325)
Affinity DataKi:  3.47E+4nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase assessed as inhibition constant for free enzyme-inhibitor complex by measuring reduction in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526627((-)-Silychristin | CHEMBL589325)
Affinity DataKi:  3.55E+4nMAssay Description:Mixed type inhibition of diphenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA substrate by UV-Vis s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526627((-)-Silychristin | CHEMBL589325)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of monophenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-Tyrosine substrate by UV-Vis spectr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526627((-)-Silychristin | CHEMBL589325)
Affinity DataIC50:  4.49E+4nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA substrate by UV-Vis spectrophoto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed