BDBM50526753 CHEMBL4457668::US10807974, Example 138::US10995088, Example 138

SMILES Cc1ccc(cc1)-c1cc(ccc1S(C)(=O)=O)S(=O)(=O)c1cnc(CN)s1

InChI Key InChIKey=IYRKKXSVEHZILX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50526753   

TargetLysyl oxidase homolog 2(Human)
The Institute of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM50526753(CHEMBL4457668 | US10807974, Example 138 | US109950...)
Affinity DataIC50: 260nMAssay Description:10. Incubate for 1 hr at room temp on a plate shaker, protected from light.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

TargetLysyl oxidase homolog 2(Human)
The Institute of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM50526753(CHEMBL4457668 | US10807974, Example 138 | US109950...)
Affinity DataIC50: 260nMAssay Description:LOXL2 batch is obtained from R&D systems/Bio-techne. Incubate for 1 hour at room temp on a plate shaker.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetLysyl oxidase homolog 2(Human)
The Institute of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM50526753(CHEMBL4457668 | US10807974, Example 138 | US109950...)
Affinity DataIC50: 423nMAssay Description:Inhibition of human C-terminal His10-tagged LOXL2 (Met1 to Gln774 residues) expressed in mouse NS0 cells using cadaverine hydrochloride as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed