BDBM50527523 CHEMBL4461658

SMILES COc1ccc(C2=NN(C3CN(c4nc(N)nc5sccc45)C3)C(=O)[C@@H]3CC=CC[C@H]23)cc1OC

InChI Key InChIKey=TZSRFHRXKKCOOX-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50527523   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
University of Antwerp

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50527523BDBM50527523(CHEMBL4461658)
Affinity DataKi:  1.20nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma brucei)
University of Antwerp

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50527523BDBM50527523(CHEMBL4461658)
Affinity DataKi:  275nMAssay Description:Inhibition of Trypanosoma brucei PDEB1 (565 to 918 residues) expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed