BDBM50527534 CHEMBL4472307

SMILES COc1ccc(C2=NN(C3CCN(c4nc(N)c5sccc5n4)CC3)C(=O)[C@@H]3CC=CC[C@H]23)cc1OC

InChI Key InChIKey=SOFFPXUEJHXWFX-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50527534   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
University of Antwerp

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50527534BDBM50527534(CHEMBL4472307)
Affinity DataKi:  0.676nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma brucei)
University of Antwerp

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50527534BDBM50527534(CHEMBL4472307)
Affinity DataKi:  339nMAssay Description:Inhibition of Trypanosoma brucei PDEB1 (565 to 918 residues) expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed