BDBM50527903 CHEMBL4530245

SMILES CO[C@@H]1O[C@@H](COP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H](O)[C@@H]1OP(O)(O)=O

InChI Key InChIKey=FEIBEUSVPXWRQR-UHFFFAOYSA-N

Data  2 Kd  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50527903   

TargetInositol 1,4,5-trisphosphate receptor type 1(Rat)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50527903(CHEMBL4530245)
Affinity DataKd:  549nMAssay Description:Displacement of [3H]-IP3 from IP3R1 in Wistar rat cerebellar membrane measured after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetInositol 1,4,5-trisphosphate receptor type 1(Rat)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50527903(CHEMBL4530245)
Affinity DataKd:  550nMAssay Description:Displacement of [3H]-IP3 from IP3R1 in Wistar rat cerebellar membrane measured after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetInositol 1,4,5-trisphosphate receptor type 1(Rat)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50527903(CHEMBL4530245)
Affinity DataEC50:  1.04E+5nMAssay Description:Partial agonist activity at rat IP3R1 expressed in HEK cells assessed as increase in calcium release in cytosol by measuring fluorescence signal by M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetInositol 1,4,5-trisphosphate receptor type 1(Rat)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50527903(CHEMBL4530245)
Affinity DataEC50:  1.05E+5nMAssay Description:Partial agonist activity at rat IP3R1 expressed in HEK cells assessed as increase in calcium release in cytosol by measuring fluorescence signal by M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed