BDBM50528228 CHEMBL4573380

SMILES Fc1ccc(Oc2ccc3nc(NC(=O)C4CC4)sc3c2)cc1NC(=O)Cc1cccc(c1)C#N

InChI Key InChIKey=DWKAWEVEZABLJA-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50528228   

TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50528228(CHEMBL4573380)
Affinity DataKd:  120nMAssay Description:Binding affinity to wild-type human partial length RIPK3 (M1 to Q307 residues) expressed in bacterial expression system after 1 hr by quantitative PC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50528228(CHEMBL4573380)
Affinity DataKd:  780nMAssay Description:Binding affinity to wild-type human partial length RIPK1 (M1 to K305 residues) expressed in bacterial expression system after 1 hr by quantitative PC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed