BDBM50528488 CHEMBL4440752
SMILES Nc1nc(SCc2cccnc2)c(C#N)c(-c2ccco2)c1C#N
InChI Key InChIKey=RCHMOBFVVHVEGJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50528488
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]DPCPX from human A1AR expressed in CHO cell membranes measured after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Displacement of [3H]ZM241385 from human A2AR expressed in CHO cell membranes measured after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 948nMAssay Description:Displacement of [125I]ABMECA from human A3R expressed in CHO cell membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human A2B expressed in CHO cells assessed as stimulation of cAMP production by alphascreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Antagonist activity at human A2AR expressed in CHO cells assessed as inhibition of CGS21680-stimulated cAMP production by alphascreen assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.70nMAssay Description:Inverse agonist activity at human A1AR expressed in CHO cells assessed as increase in forskolin-stimulated cAMP production by alphascreen assayMore data for this Ligand-Target Pair