BDBM50529069 CHEMBL4476294

SMILES Fc1ccc2[nH]cc(CCCN3CCN(CC3)c3nsc4ccccc34)c2c1

InChI Key InChIKey=JEVQGJKCQNMIHY-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50529069   

Target5-hydroxytryptamine receptor 1A(Human)
China State Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50529069(CHEMBL4476294)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor (unknown origin) expressed in HEK293 cells membranes incubated for 60 mins by scintillation counti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Human)
China State Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50529069(CHEMBL4476294)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) expressed in CHO cell membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rat)
China State Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50529069(CHEMBL4476294)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of rat synaptosomes 5HT transporter assessed as reduction in [3H]serotonin reuptake incubated for 15 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed