BDBM50529874 CHEMBL4584762

SMILES Cc1ccc(NC(=O)Nc2ccc(Cc3ccncc3)cc2)cc1C

InChI Key InChIKey=PWYKURSOQPCEIO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50529874   

TargetCyclin-C(Human)
Shaoxing University

Curated by ChEMBL
LigandPNGBDBM50529874(CHEMBL4584762)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human full-length GST/His-fused CDK8/CycC expressed in Sf9 insect cells using RBER-IRStide as substrate after 1 hr in prese...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Shaoxing University

Curated by ChEMBL
LigandPNGBDBM50529874(CHEMBL4584762)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human full-length GST/His-fused CDK8/CycC expressed in Sf9 insect cells using RBER-IRStide as substrate after 1 hr in prese...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed