BDBM50530012 CHEMBL4558007

SMILES CC#CCn1c(cc(=O)n(Cc2cc(Br)ccc2C(O)=O)c1=O)N1CCC[C@@H](N)C1

InChI Key InChIKey=FYTNHPZZMNRUBG-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50530012   

TargetDipeptidyl peptidase 4(Human)
Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50530012(CHEMBL4558007)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant human DPP4 expressed in baculovirus infected Sf9 insect cells using Gly-Pro-AMC as substrate measured at 60 secs interval f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50530012(CHEMBL4558007)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant human DPP4 expressed in baculovirus infected Sf9 insect cells using Gly-Pro-AMC as substrate measured at 60 secs interval f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50530012(CHEMBL4558007)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full-length human N-terminal GST-tagged DPP9 expressed in Sf9 insect cells using Gly-Pro-AMC as substrate measured at 60 se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50530012(CHEMBL4558007)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full-length human N-terminal GST-tagged DPP8 expressed in Sf9 insect cells using Gly-Pro-AMC as substrate measured at 60 se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50530012(CHEMBL4558007)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full-length human N-terminal GST-tagged DPP8 expressed in Sf9 insect cells using Gly-Pro-AMC as substrate measured at 60 se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50530012(CHEMBL4558007)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full-length human N-terminal GST-tagged DPP9 expressed in Sf9 insect cells using Gly-Pro-AMC as substrate measured at 60 se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed