BDBM50530499 CHEMBL4449685
SMILES Cc1cc2c(cc1-c1cc3cc(C(O)=O)c(=O)oc3cc1O)C(C)(C)CCC2(C)C
InChI Key InChIKey=UYPOSIGCFZMVDD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50530499
TargetRetinoic acid receptor RXR-alpha(Human)
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataKi: 230nMAssay Description:Displacement of 9-cis-[11,12-3H]-retinoic acid from human RXRalpha LBD incubated for overnight by scintillation counting methodMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Human)
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataKi: 230nMAssay Description:Displacement of 9-cis-[11,12-3H]-retinoic acid from human RXRalpha LBD incubated for overnight by scintillation counting methodMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Human)
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataKd: 1.11E+3nMAssay Description:Binding affinity to human RXRalpha-LBD (224 to 462 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociation constant using PGC-1al...More data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Human)
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataEC50: 22nMAssay Description:Agonist activity at human RXRalpha LBD expressed in African green monkey COS1 cells incubated for 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Human)
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataKd: 1.32E+4nMAssay Description:Binding affinity to human RXRalpha-LBD (224 to 462 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociation constant using SRC1 as...More data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Human)
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataKd: 233nMAssay Description:Binding affinity to human RXRalpha LBD incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Human)
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataEC50: 22nMAssay Description:Agonist activity at human RXRalpha LBD expressed in African green monkey COS1 cells incubated for 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Human)
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataKd: 233nMAssay Description:Binding affinity to human RXRalpha LBD incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair