BDBM50531178 CHEMBL4546517

SMILES [H][C@@]12CCc3cc(C(C)C)c(O)c(O)c3[C@]1(CCCC2(C)C)c1nnc(o1)[C@H](C)NCO

InChI Key InChIKey=RBPXDDKOZBAQRF-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50531178   

TargetFarnesyl pyrophosphate synthase(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531178(CHEMBL4546517)
Affinity DataIC50: 190nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) using GPP and IPP as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531178(CHEMBL4546517)
Affinity DataIC50: 190nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) using GPP and IPP as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531178(CHEMBL4546517)
Affinity DataIC50: 194nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) using GPP and IPP as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531178(CHEMBL4546517)
Affinity DataIC50: 194nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) using GPP and IPP as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531178(CHEMBL4546517)
Affinity DataIC50: 620nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) assessed as using GPP and I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531178(CHEMBL4546517)
Affinity DataIC50: 620nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) assessed as using GPP and I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531178(CHEMBL4546517)
Affinity DataIC50: 4.32E+4nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged GGPPS expressed in Escherichia coli BL21 (DE3) using FPP and [14C] IPP as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531178(CHEMBL4546517)
Affinity DataIC50: 4.32E+4nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged GGPPS expressed in Escherichia coli BL21 (DE3) using FPP and [14C] IPP as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed