BDBM50531185 CHEMBL4472267

SMILES [H][C@@]12CC3OC[C@@]1(CCCC2(C)C)C1=C3C=C(C(C)C)C(=O)C1=O

InChI Key InChIKey=MCRKHQBQOAINHY-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50531185   

TargetFarnesyl pyrophosphate synthase(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531185(CHEMBL4472267)
Affinity DataIC50: 230nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) assessed as using GPP and I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531185(CHEMBL4472267)
Affinity DataIC50: 230nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) assessed as using GPP and I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531185(CHEMBL4472267)
Affinity DataIC50: 596nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) using GPP and IPP as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531185(CHEMBL4472267)
Affinity DataIC50: 596nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) using GPP and IPP as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531185(CHEMBL4472267)
Affinity DataIC50: 600nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) using GPP and IPP as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531185(CHEMBL4472267)
Affinity DataIC50: 600nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) using GPP and IPP as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531185(CHEMBL4472267)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) using GPP and [14C] IPP as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531185(CHEMBL4472267)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) using GPP and [14C] IPP as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531185(CHEMBL4472267)
Affinity DataIC50: 1.69E+4nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged GGPPS expressed in Escherichia coli BL21 (DE3) using FPP and [14C] IPP as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50531185(CHEMBL4472267)
Affinity DataIC50: 1.69E+4nMAssay Description:Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged GGPPS expressed in Escherichia coli BL21 (DE3) using FPP and [14C] IPP as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed