BDBM50531582 CHEMBL4463035

SMILES CNC(=O)C[C@H]1COc2cc(F)c(CC(C)C)cc2N1C(=O)c1ccnc(NC(N)=O)c1

InChI Key InChIKey=NVMGBEWNMCNKHG-HNNXBMFYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50531582   

TargetMineralocorticoid receptor(Human)
Pharmaron-Beijing

Curated by ChEMBL
LigandPNGBDBM50531582(CHEMBL4463035)
Affinity DataKi:  7.90nMAssay Description:Displacement of [3H]-aldosterone to human mineralocorticoid receptor LBD by radiometric binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Pharmaron-Beijing

Curated by ChEMBL
LigandPNGBDBM50531582(CHEMBL4463035)
Affinity DataKi:  126nMAssay Description:Binding affinity to recombinant human GR LBD by fluormone GS red-fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetMineralocorticoid receptor(Human)
Pharmaron-Beijing

Curated by ChEMBL
LigandPNGBDBM50531582(CHEMBL4463035)
Affinity DataIC50:  100nMAssay Description:Antagonist activity at gal4-fused human mineralocorticoid receptor LBD expressed in UAS-MR-bla HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed