BDBM50531747 CHEMBL4459732

SMILES Fc1ccccc1-c1cn(Cc2ccc(cc2)-c2cncnc2)nn1

InChI Key InChIKey=MXEHLGSSZLWMBO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50531747   

TargetEphrin type-B receptor 4(Human)
The First Affiliated Hospital of Xi'An Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50531747BDBM50531747(CHEMBL4459732)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of EphB4 (unknown origin) after 1 hrs by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
The First Affiliated Hospital of Xi'An Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50531747BDBM50531747(CHEMBL4459732)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of Tie-2 (unknown origin) after 1 hrs by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
The First Affiliated Hospital of Xi'An Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50531747BDBM50531747(CHEMBL4459732)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of VEGFR-2 (unknown origin) after 1 hrs by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed