BDBM50531748 CHEMBL4452405

SMILES Cc1ccc(cc1)-c1cn(Cc2ccc(cc2)-c2cncnc2)nn1

InChI Key InChIKey=JYLMIXWMBBGQSD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50531748   

TargetVascular endothelial growth factor receptor 2(Human)
The First Affiliated Hospital of Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50531748(CHEMBL4452405)
Affinity DataIC50:  11nMAssay Description:Inhibition of VEGFR-2 (unknown origin) after 1 hrs by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Human)
The First Affiliated Hospital of Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50531748(CHEMBL4452405)
Affinity DataIC50:  26nMAssay Description:Inhibition of Tie-2 (unknown origin) after 1 hrs by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Human)
The First Affiliated Hospital of Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50531748(CHEMBL4452405)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of EphB4 (unknown origin) after 1 hrs by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed