BDBM50531974 CHEMBL4575018

SMILES CCCCc1ccc(cc1)C(=O)C1CCN(CC1)C(=O)c1cc(O)ccc1F

InChI Key InChIKey=NCCCUONVHAETDD-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50531974   

TargetMonoglyceride lipase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50531974(CHEMBL4575018)
Affinity DataIC50: 74nMAssay Description:Inhibition of human recombinant MAGL using 4-NPA as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50531974(CHEMBL4575018)
Affinity DataIC50: 431nMAssay Description:Inhibition of MAGL in human U937 cell homogenates incubated for 5 mins in presence of [1,2,3-3H]2-OG by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50531974(CHEMBL4575018)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]CP55,940 to human CB2 receptor expressed in cell membranes after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetLysophosphatidylserine lipase ABHD12(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50531974(CHEMBL4575018)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ABHD12 expressed in HEK293 cell homogenates pre-incubated for 30 mins in presence of [1,2,3-3H]2-OG by liquid scintillation spect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50531974(CHEMBL4575018)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cell homogenates using [ethanolamine-1-3H]AEA as substrate after 15 mins by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetMonoacylglycerol lipase ABHD6(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50531974(CHEMBL4575018)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cell homogenates pre-incubated for 30 mins in presence of [1,2,3-3H]2-OG by liquid scintillation spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50531974(CHEMBL4575018)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]CP55,940 to human CB1 receptor expressed in cell membranes after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed