BDBM50532175 CHEMBL4436444::US20240139197, Compound 11

SMILES CCCCCCN(C)Cc1cccc(c1)-c1[nH]c2c(cnn2c(=O)c1C(C)C)C#N

InChI Key InChIKey=OHXZVGXBNAAWBB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50532175   

TargetLysine-specific demethylase 5A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50532175(CHEMBL4436444 | US20240139197, Compound 11)
Affinity DataIC50: 65nMAssay Description:Inhibition of human C-terminal FLAG-tagged KDM5A (1 to 1090 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K4(Me3)-GGK(Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50532175(CHEMBL4436444 | US20240139197, Compound 11)
Affinity DataIC50: 65.3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2024
Entry Details
US Patent