BDBM50532350 CHEMBL4571067

SMILES Cc1cc(Nc2nccc(n2)-c2ccn([C@H](CO)c3ccc(Cl)c(F)c3)c(=O)c2)ccn1

InChI Key InChIKey=WZYSLGBCMSEWCH-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50532350   

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50532350(CHEMBL4571067)
Affinity DataIC50: 0.940nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50532350(CHEMBL4571067)
Affinity DataIC50: 0.940nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 3(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50532350(CHEMBL4571067)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 3(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50532350(CHEMBL4571067)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50532350(CHEMBL4571067)
Affinity DataIC50: 340nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50532350(CHEMBL4571067)
Affinity DataIC50: 340nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed