BDBM50532688 CHEMBL4464014

SMILES Cc1cc(ccn1)-c1n[nH]c2cc(NS(=O)(=O)NCc3ccccc3)ncc12

InChI Key InChIKey=FPWWAEKIUQVAOY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50532688   

TargetMitogen-activated protein kinase 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50532688(CHEMBL4464014)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human ERK2 preincubated for 15 mins followed by addition of IMAP peptide substrate and ATP measured after 60 mins by IMAP-FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50532688(CHEMBL4464014)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human ERK2 preincubated for 15 mins followed by addition of IMAP peptide substrate and ATP measured after 60 mins by IMAP-FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed