BDBM50532710 CHEMBL4449242

SMILES COc1cc2CCN(Cc3ccc(cc3)-c3ccc(OCCCOc4nonc4C)cc3)Cc2cc1OC

InChI Key InChIKey=KEIBDNCEUNQCGA-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50532710   

TargetATP-dependent translocase ABCB1(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50532710(CHEMBL4449242)
Affinity DataEC50:  350nMAssay Description:Inhibition of MDR1 (unknown origin) expressed in MDCK cells assessed as decrease in calcein-AM transport after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50532710(CHEMBL4449242)
Affinity DataEC50:  350nMAssay Description:Inhibition of MDR1 (unknown origin) expressed in MDCK cells assessed as decrease in calcein-AM transport after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed