BDBM50533136 CHEMBL4540197
SMILES CCCn1c(SCC(=O)Nc2nc3ccc(OC)cc3s2)nnc1-c1ccncc1
InChI Key InChIKey=JIUFLMSAFMXEEC-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50533136
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Displacement of [3H]-GNF-1331 from human PORCN after 3 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Displacement of [3H]-GNF-1331 from human PORCN after 3 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair