BDBM50533140 CHEMBL4524961

SMILES COc1ccc2nc(sc2c1)C(=O)NCc1ccc(cc1)-c1ccncc1

InChI Key InChIKey=AIMNWWXTCPIRLB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50533140   

TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50533140(CHEMBL4524961)
Affinity DataIC50:  380nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50533140(CHEMBL4524961)
Affinity DataIC50:  380nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed