BDBM50533234 CHEMBL4437930

SMILES Fc1cc(F)c(cc1Cl)-c1cc(Nc2ccncc2)c2cc[nH]c2n1

InChI Key InChIKey=MOXKDKRBVAMLRS-UHFFFAOYSA-N

Data  8 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50533234   

TargetCytochrome P450 2C8(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50533234(CHEMBL4437930)
Affinity DataIC50:  100nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCytochrome P450 1A2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50533234(CHEMBL4437930)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetTGF-beta receptor type-1(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50533234(CHEMBL4437930)
Affinity DataEC50:  20nMAssay Description:Inhibition of ALK5 in TGF beta1-stimulated HEK293T cells by SMAD binding element-driven beta lactamase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetTGF-beta receptor type-1(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50533234(CHEMBL4437930)
Affinity DataIC50:  40nMAssay Description:Inhibition of ALK5 (unknown origin) using fluorescein-labeled peptide substrate incubated for 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50533234(CHEMBL4437930)
Affinity DataIC50: <794nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetTGF-beta receptor type-1(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50533234(CHEMBL4437930)
Affinity DataEC50:  20nMAssay Description:Inhibition of ALK5 in TGF beta1-stimulated HEK293T cells by SMAD binding element-driven beta lactamase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetTGF-beta receptor type-1(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50533234(CHEMBL4437930)
Affinity DataIC50:  40nMAssay Description:Inhibition of ALK5 (unknown origin) using fluorescein-labeled peptide substrate incubated for 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCytochrome P450 2C8(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50533234(CHEMBL4437930)
Affinity DataIC50:  100nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50533234(CHEMBL4437930)
Affinity DataIC50: <794nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCytochrome P450 1A2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50533234(CHEMBL4437930)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed