BDBM50533345 CHEMBL4468676

SMILES CCn1c2ccccc2n([C@@H]2CCN(C[C@H]2CO)C2CCCCCCC2)c1=O

InChI Key InChIKey=GAHHIVYSBCUTKD-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50533345   

TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50533345(CHEMBL4468676)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]nociceptin from recombinant human nociceptin opioid receptor expressed in CHO cell membranes after 60 mins by scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50533345(CHEMBL4468676)
Affinity DataIC50: 5.30nMAssay Description:Antagonist activity at human nociceptin opioid receptor expressed in CHO cell membranes after 2.5 hrs by GTPgamma(35)S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50533345(CHEMBL4468676)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]DAMGO from recombinant human mu opioid receptor expressed in CHO cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed