BDBM50533401 CHEMBL4445181

SMILES Cc1ccc(cc1)-c1ccc(Nc2cc(=O)n(O)c(=O)n2C)cc1

InChI Key InChIKey=ZVKWPGKFSDNUEQ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50533401   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50533401(CHEMBL4445181)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of re-constituted HIV1 reverse transcriptase RNase H domain fragmentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetTripartite terminase subunit 3(HHV-5)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50533401(CHEMBL4445181)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of Human Cytomegalovirus C-terminal UL89 phosphorylation using (5-tcggtgcgggcctcttcgctattacgccagctggcgaaagggggatgtgctgcaaggcga as a substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50533401(CHEMBL4445181)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetTripartite terminase subunit 3(HHV-5)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50533401(CHEMBL4445181)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human cytomegalovirus pUL89 endonuclease activity using 60 bp dsDNA substrate incubated for 30 mins by ELISA-based biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50533401(CHEMBL4445181)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in DNA 3'-end cleavage using HTS2 substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50533401(CHEMBL4445181)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in RNA 5'-end directed cleavage using HTS3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed