BDBM50533536 CHEMBL4483694

SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](CSSC[C@H]2NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H]3CCCN3C(=O)[C@@H]3CSSC[C@@H](NC(=O)[C@H](Cc4ccc(O)cc4)NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC1=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N3)NC(=O)[C@@H](NC2=O)[C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(O)=O)NC(=O)[C@@H](NC(=O)CNC(=O)CN)C(C)C

InChI Key InChIKey=IWNWXPRWSFWNMU-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50533536   

TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50533536(CHEMBL4483694)
Affinity DataKi:  0.160nMAssay Description:Inhibition of trypsin (unknown origin) using Bz-FVRpNA as substrate incubated for 30 mins measured for 7 mins by morrison plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50533536(CHEMBL4483694)
Affinity DataKi:  28nMAssay Description:Inhibition of plasmin (unknown origin) using Ac-RM(O2)YRpNA as substrate incubated for 30 mins measured for 7 mins by morrison plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50533536(CHEMBL4483694)
Affinity DataKi:  750nMAssay Description:Inhibition of factor 12a (unknown origin) using Ac-QRFRpNA as substrate incubated for 30 mins measured for 7 mins by morrison plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProthrombin(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50533536(CHEMBL4483694)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of thrombin (unknown origin) using Ac-ATPRpNA as substrate incubated for 30 mins measured for 7 mins by morrison plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50533536(CHEMBL4483694)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of factor 10a (unknown origin) using Ac-QRSRpNA as substrate incubated for 30 mins measured for 7 mins by morrison plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCoagulation factor IX(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50533536(CHEMBL4483694)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of factor 9a (unknown origin) using Ac-QGRpNA as substrate incubated for 30 mins measured for 7 mins by morrison plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50533536(CHEMBL4483694)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of tPA (unknown origin) incubated for 30 mins measured for 7 mins by morrison plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50533536(CHEMBL4483694)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of uPA (unknown origin) incubated for 30 mins measured for 7 mins by morrison plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50533536(CHEMBL4483694)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human plasma kallikrein using Ac-RM(O2)YRpNA as substrate incubated for 30 mins measured for 7 mins by morrison plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50533536(CHEMBL4483694)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of factor 11a (unknown origin) using Bz-FVRpNA as substrate incubated for 30 mins measured for 7 mins by morrison plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed