BDBM50533537 CHEMBL4590811
SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](CSSC[C@H]2NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H]3CCCN3C(=O)[C@@H]3CSSC[C@@H](NC(=O)[C@H](Cc4ccc(O)cc4)NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc4c[nH]c5ccccc45)NC1=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N3)NC(=O)[C@@H](NC2=O)[C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H](N)CCCCN
InChI Key InChIKey=JEBHEQAGJNWHLB-OOUDVJKPSA-N
Data 10 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50533537
Affinity DataKi: 490nMAssay Description:Inhibition of factor 12a (unknown origin) using Ac-QRFRpNA as substrate incubated for 30 mins measured for 7 mins by morrison plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 4.54E+3nMAssay Description:Inhibition of plasmin (unknown origin) using Ac-RM(O2)YRpNA as substrate incubated for 30 mins measured for 7 mins by morrison plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 6.24E+3nMAssay Description:Inhibition of trypsin (unknown origin) using Bz-FVRpNA as substrate incubated for 30 mins measured for 7 mins by morrison plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of factor 9a (unknown origin) using Ac-QGRpNA as substrate incubated for 30 mins measured for 7 mins by morrison plot analysisMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of uPA (unknown origin) incubated for 30 mins measured for 7 mins by morrison plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human plasma kallikrein using Ac-RM(O2)YRpNA as substrate incubated for 30 mins measured for 7 mins by morrison plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of thrombin (unknown origin) using Ac-ATPRpNA as substrate incubated for 30 mins measured for 7 mins by morrison plot analysisMore data for this Ligand-Target Pair
TargetTissue-type plasminogen activator(Homo sapiens (Human))
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of tPA (unknown origin) incubated for 30 mins measured for 7 mins by morrison plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of factor 11a (unknown origin) using Bz-FVRpNA as substrate incubated for 30 mins measured for 7 mins by morrison plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of factor 10a (unknown origin) using Ac-QRSRpNA as substrate incubated for 30 mins measured for 7 mins by morrison plot analysisMore data for this Ligand-Target Pair