BDBM50533568 CHEMBL4466610::US11459295, Compound LM5750B 8a
SMILES CC[C@H](C(O)=O)c1ccc2cc(OC)ccc2c1
InChI Key InChIKey=LSDAHSHHKKHOKE-UHFFFAOYSA-N
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50533568
TargetAldo-keto reductase family 1 member C3(Human)
The Trustees of The University of Pennsylvania
US Patent
The Trustees of The University of Pennsylvania
US Patent
Affinity DataIC50: 50nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Human)
The Trustees of The University of Pennsylvania
US Patent
The Trustees of The University of Pennsylvania
US Patent
Affinity DataIC50: 110nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Human)
The Trustees of The University of Pennsylvania
US Patent
The Trustees of The University of Pennsylvania
US Patent
Affinity DataIC50: 110nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Human)
The Trustees of The University of Pennsylvania
US Patent
The Trustees of The University of Pennsylvania
US Patent
Affinity DataIC50: 120nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Human)
The Trustees of The University of Pennsylvania
US Patent
The Trustees of The University of Pennsylvania
US Patent
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant AKR1C3 using S-tetralol as substrate assessed as reduction in NADP+-dependent S-tetralol oxidation preincubated for 1...More data for this Ligand-Target Pair
Affinity DataIC50: 1.72E+3nMAssay Description:Inhibition of human recombinant AKR1C2 using S-tetralol as substrate assessed as reduction in NADP+-dependent S-tetralol oxidation preincubated for 1...More data for this Ligand-Target Pair
Affinity DataIC50: 1.93E+3nMAssay Description:The effect of the compounds on COX-1 activity was determined by a continuous colorimetric assay that monitored the oxidation of N, N, N, N-tetramethy...More data for this Ligand-Target Pair
Affinity DataIC50: 1.93E+3nMAssay Description:Inhibition of COX1 in ram seminal vesicles using arachidonic acid as substrate assessed as reduction in PGH2 conversion to PGG2 by measuring TMPD oxi...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:The effect of the compounds on COX-1 activity was determined by a continuous colorimetric assay that monitored the oxidation of N, N, N, N-tetramethy...More data for this Ligand-Target Pair
Affinity DataIC50: 4.81E+4nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:The effect of the compounds on COX-1 activity was determined by a continuous colorimetric assay that monitored the oxidation of N, N, N, N-tetramethy...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:The effect of the compounds on COX-1 activity was determined by a continuous colorimetric assay that monitored the oxidation of N, N, N, N-tetramethy...More data for this Ligand-Target Pair