BDBM50533815 CHEMBL4434704

SMILES COc1ccc2c(c1)C(=Cc1ccc3c(-c4ccc(N5CCN(C)CC5)nc4)n[nH]c3c1)C(=O)N2

InChI Key InChIKey=TVRYEYSLCUPRPL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50533815   

TargetSerine/threonine-protein kinase PLK4(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50533815BDBM50533815(CHEMBL4434704)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of PLK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50533815BDBM50533815(CHEMBL4434704)
Affinity DataIC50: 28nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50533815BDBM50533815(CHEMBL4434704)
Affinity DataIC50: 35nMAssay Description:Inhibition of AURKB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50533815BDBM50533815(CHEMBL4434704)
Affinity DataIC50: 630nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50533815BDBM50533815(CHEMBL4434704)
Affinity DataIC50: 700nMAssay Description:Inhibition of AURKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed