BDBM50533901 CHEMBL4460880

SMILES COC(=O)c1cccc(CN2CCN(CC2)c2c(C)n(Cc3c(F)cccc3C(F)(F)F)c(=O)n(C[C@H](N)c3ccccc3)c2=O)c1

InChI Key InChIKey=PYKVFAZOAXOAOZ-LJAQVGFWSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50533901   

TargetGonadotropin-releasing hormone receptor(Human)
Sk Chemicals

Curated by ChEMBL
LigandPNGBDBM50533901(CHEMBL4460880)
Affinity DataIC50:  0.390nMAssay Description:Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Human)
Sk Chemicals

Curated by ChEMBL
LigandPNGBDBM50533901(CHEMBL4460880)
Affinity DataIC50:  23nMAssay Description:Antagonist activity against human GnRH receptor expressed in HEK293 cells co-transfected with pGL4-NFAT promoter AP1-luc assessed as inhibition of 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed