BDBM50534272 CHEMBL4593409

SMILES C[C@H](Cc1cccc(c1)-c1cc(Cc2ccccc2)ccc1C(N)=O)C(O)=O

InChI Key InChIKey=PXRCDPVYRPKGGI-MRXNPFEDSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50534272   

TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50534272(CHEMBL4593409)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant sPLA2-2A (unknown origin) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate preincubated for 10 mins foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGroup 10 secretory phospholipase A2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50534272(CHEMBL4593409)
Affinity DataIC50:  400nMAssay Description:Inhibition of recombinant sPLA2-10 (unknown origin) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate preincubated for 10 mins foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGroup XIIB secretory phospholipase A2-like protein(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50534272(CHEMBL4593409)
Affinity DataIC50: <14nMAssay Description:Inhibition of sPLA2 in human HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGroup XIIB secretory phospholipase A2-like protein(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50534272(CHEMBL4593409)
Affinity DataIC50:  56nMAssay Description:Inhibition of sPLA2 in atherosclerotic plaque from coronary artery disease patientMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed