BDBM50534349 CHEMBL4447800

SMILES Cc1ccc2nc(sc2c1S(O)(=O)=O)-c1ccc2nc(sc2c1)-c1ccc(NC(=O)c2ccc3nc(sc3c2)-c2ccc(N)cc2)cc1

InChI Key InChIKey=FUALGAHMNLHVEV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50534349   

TargetGenome polyprotein(DENV-2)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50534349(CHEMBL4447800)
Affinity DataIC50: 500nMAssay Description:Inhibition of Dengue virus 2 NS3 helicase incubated for 2 mins followed by ATP additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetGenome polyprotein(DENV-2)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50534349(CHEMBL4447800)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of RNA unwinding activity of thioredoxin/His6 tagged Dengue virus 2 TSV01 NS3 helicase (171 to 618 residues) expressed in Escherichia coli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed