BDBM50534363 CHEMBL2151090

SMILES CCN(CC)c1ccc(Nc2nc(cs2)-c2ccc(cc2)-n2ccnc2)c(C)c1

InChI Key InChIKey=ZAYVDODIKJTELC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50534363   

TargetPresenilin-1(Human)
Forum Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50534363(CHEMBL2151090)
Affinity DataEC50:  1.50E+3nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells expressing human APP751 assessed as reduction in amyloid beta 42 production after 18 to 22 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed