BDBM50535290 CHEMBL4444849

SMILES COc1cccc(\C=N\C2CCN(Cc3ccccc3)CC2)c1OC

InChI Key InChIKey=GGLDJGOCUBPSEY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50535290   

TargetBeta-secretase 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50535290(CHEMBL4444849)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50535290(CHEMBL4444849)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of human BACE1 using as 7-Methoxycoumarin-4-acetyl-[Asn670, Leu671]-Amyloid beta/A4 precursor protein 770 fragment 667-676-(2,4-dinitrophe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50535290(CHEMBL4444849)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of GSK-3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandPNGBDBM50535290(CHEMBL4444849)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human erythrocyte acetylcholinesterase using acetylthiocholine iodide as substrate pre-incubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandPNGBDBM50535290(CHEMBL4444849)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human serum butyrylcholinesterase using BTCI as substrate pre-incubated for 10 mins followed by substrate addition and measured for 6 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed