BDBM50535369 CHEMBL4461163

SMILES CC(C)c1onc(c1COc1ccc(COc2ccc(cc2)C#N)cc1)-c1c(Cl)cccc1Cl

InChI Key InChIKey=NGAUKUZWMRSOHR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50535369   

TargetBile acid receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535369(CHEMBL4461163)
Affinity DataEC50:  940nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed