BDBM50535378 CHEMBL4562865

SMILES COC(=O)c1cccc(c1)-c1ccc(OCc2c(onc2-c2c(Cl)cccc2Cl)C(C)C)cc1

InChI Key InChIKey=RHVBKJAWIAEAHW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50535378   

TargetBile acid receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535378(CHEMBL4562865)
Affinity DataEC50:  2.80E+3nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed