BDBM50535379 CHEMBL4445722
SMILES CC(C)c1onc(c1COc1ccc(cc1)-c1cccc(c1)C(O)=O)-c1c(Cl)cccc1Cl
InChI Key InChIKey=KKSDGBPWVCMNGH-UHFFFAOYSA-N
Data 1 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50535379
Affinity DataEC50: 1.40E+3nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+3nMAssay Description:Inhibition of GSK3beta-mediated CRMP-2 phosphorylation by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+3nMAssay Description:Tested for Farnesyl Transferase Inhibition to displace 50% of radiolabeled Farnesyltransferase inhibitors from Farnesyltransferase in v-Ha-ras-transf...More data for this Ligand-Target Pair
Affinity DataEC50: 2.30E+3nMAssay Description:Inhibition of BACE1 expressed in HEK cells by cell-based assayMore data for this Ligand-Target Pair
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"
Curated by ChEMBL
University of Naples "Federico II"
Curated by ChEMBL
Affinity DataIC50: 4.97E+3nMAssay Description:Inhibition of GSK3beta-mediated CRMP-2 phosphorylation by cell based assayMore data for this Ligand-Target Pair
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"
Curated by ChEMBL
University of Naples "Federico II"
Curated by ChEMBL
Affinity DataIC50: 4.97E+3nMAssay Description:Inhibition of BACE1 assessed as inhibition of amyloid beta-40 production by cell based assayMore data for this Ligand-Target Pair
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"
Curated by ChEMBL
University of Naples "Federico II"
Curated by ChEMBL
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of human ERG by cell-based patch clamp methodMore data for this Ligand-Target Pair