BDBM50535653 CHEMBL4530832

SMILES OC(=O)c1ccc(cc1)C(=O)N1CCc2nc([nH]c(=O)c2C1)-c1ccccc1

InChI Key InChIKey=FHOQQEJYCXYRNT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50535653   

LigandPNGBDBM50535653(CHEMBL4530832)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of recombinant MTHFD2 (unknown origin) assessed as reduction in methenyl-THF formation using tetrahydrofolate, NAD and formaldehyde incuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-1-tetrahydrofolate synthase, cytoplasmic(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50535653(CHEMBL4530832)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of recombinant MTHFD1 (unknown origin) assessed as reduction in methenyl-THF formation using tetrahydrofolate, NADP and formaldehyde incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed