BDBM50535759 CHEMBL4471843

SMILES O=C1NC(=O)C(=O)c2sc(cc12)-c1ccccc1

InChI Key InChIKey=IMDNSVLQVQIAKK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50535759   

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50535759(CHEMBL4471843 | US12227515, Compound 3)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human His-6-tagged PTP4A3 expressed in Escherichia coli assessed as reduction in hydrolysis using DIFMUP as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50535759(CHEMBL4471843 | US12227515, Compound 3)
Affinity DataIC50: 49.5nMAssay Description:Enzyme activity assays were performed in triplicate in 384-well Greiner Bio-One black small volume microtiter plates, as previously described using r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50535759(CHEMBL4471843 | US12227515, Compound 3)
Affinity DataIC50: 49.5nMAssay Description:Table 2: Recombinant human PTP4A3 phosphatase was used and the enzymatic assay was performed as previously described,20 except that it was fully auto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent