BDBM50536038 CHEMBL4592538

SMILES COc1ccc(C(=O)N2CCc3c([nH]c4ccccc34)C2c2cccc(OC)c2)cc1

InChI Key InChIKey=HQMNMYXRCMXMRT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50536038   

LigandChemical structure of BindingDB Monomer ID 50536038BDBM50536038(CHEMBL4592538)
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of human ABCG2 expressed in MDCK2 cells assessed as reduction in Hoechst 33342 efflux pre-incubated for 30 mins before Hoechst 33342 addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50536038BDBM50536038(CHEMBL4592538)
Affinity DataIC50: 3.38E+3nMAssay Description:Inhibition of ABCB1 in human A2780/ADR cells assessed as reduction in calcein AM efflux pre-incubated for 30 mins before calcein AM addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed