BDBM50536411 CHEMBL4564931
SMILES COc1ncc(cc1NS(C)(=O)=O)-c1cc2COCc2c(NC(=O)c2cccc(C)n2)c1
InChI Key InChIKey=OMDXTFNEXXOCHC-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50536411
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Glaxosmithkline R&D
Curated by ChEMBL
Glaxosmithkline R&D
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of PI3Kdelta in human PBMC assessed as reduction in cytostim-induced IFNgamma production after 20 hrs by electrochemiluminescence assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Glaxosmithkline R&D
Curated by ChEMBL
Glaxosmithkline R&D
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate preincubated for 15 mins followed by substrate addition measured after 60 mins in pr...More data for this Ligand-Target Pair